New one-hour surgery is a gamechanger for men with prostate cancer

A groundbreaking, hour-long procedure using electrical currents to eliminate hard-to-reach prostate tumors is providing renewed hope for thousands of men with prostate cancer. Known as the "Nanoknife" operation, this innovative treatment has been hailed by surgeons as a "game-changing" technique with the potential to cure the disease.

The Nanoknife procedure employs a method called irreversible electroporation, which delivers electrical pulses directly into the tumor. This approach disrupts the tumor's cell membranes without the invasiveness of traditional treatments, reducing the risk of harm to surrounding organs and tissues.

One of the most significant advantages of this technique is its ability to target tumors that are otherwise difficult to reach, opening up new treatment possibilities for prostate cancer patients.

Unlike traditional options such as radiotherapy or prostate removal surgery—which often result in complications like incontinence, urinary issues, and sexual dysfunction—Nanoknife therapy minimizes these risks.

Each year, over 50,000 men in the UK are diagnosed with prostate cancer, driving the NHS to adopt Nanoknife therapy as an alternative to conventional methods. Early results are promising, with surgeons at University College London Hospital (UCLH) performing the first six Nanoknife procedures under the NHS.

Professor Mark Emberton, a consultant urologist at UCLH, emphasized the simplicity and effectiveness of the technique. “It’s a novel way of destroying cancer cells,” he explained, adding that the procedure is easy to teach and adopt, which could make it a transformative option in cancer care.

With its shorter operation time, reduced side effects, and potential for widespread implementation, Nanoknife therapy represents a significant advancement in prostate cancer treatment, offering a less invasive and more efficient path toward a cure.

According to Emberton, Nanoknife has the capability to transform into a standard treatment for prostate cancer, unlike targeted treatments that are only accessible in major specialized centers at present.

The professor explained that day surgery can help alleviate the strain on the NHS during periods of high demand, as it eliminates the need for patients to stay overnight in hospital and allows for better utilization of operating theaters.

One of the recipients of the NHS treatment, Neil Gershon, expressed his attraction to the procedure by highlighting its lower risk of collateral damage.

He recounted his experience, saying, "It was completed in a day, which was fantastic. After the effects of the general anesthesia subsided, I felt perfectly fine, with no discomfort. It couldn't have gone any smoother."

Natalia Norori, the knowledge manager at Prostate Cancer UK, has said the therapy could ‘make a big difference to the quality of life of men diagnosed with localized prostate cancer’.

The Nanoknife, created by AngioDynamics, uses electrodes to administer quick electrical pulses that eliminate cancerous cells by enveloping the tumor.

Experts revealed that using MRI scanning to guide the short pulses makes it possible to aim at the precise area. This approach ensures that the surrounding healthy cells remain untouched and are preserved.

According to Natalia Norori, Prostate Cancer UK's knowledge manager, preliminary studies indicate that treatments like the Nanoknife could potentially cure prostate cancer while also minimizing side effects for men.

This technology is one of several focal therapy types on the horizon that have been developed to accurately target tumors and decrease damage to the rest of the prostate.

The efficacy of Nanoknife could significantly improve men's quality of life. However, larger clinical trials are necessary to determine whether it is as effective as conventional treatments.

On the first day, the UCLH team performed six procedures, including one on 70-year-old Neil Gershon.

Despite the operations at UCLH, Norori stated that larger trials are required to test the effectiveness of Nanoknife.

According to the Mayo Clinic, prostate cancer may cause no signs or symptoms in its early stages.

Prostate cancer that's more advanced may cause signs and symptoms such as:

According to the Mayo Clinic, based on current information on the subject, it's not clear what causes prostate cancer.

Doctors know that prostate cancer begins when cells in the prostate develop changes in their DNA. A cell's DNA contains the instructions that tell a cell what to do. The changes tell the cells to grow and divide more rapidly than normal cells do. The abnormal cells continue living, when other cells would die.

Prostate gland: The prostate gland is located just below the bladder in men and surrounds the top portion of the tube that drains urine from the bladder (urethra). The prostate's primary function is to produce the fluid that nourishes and transports sperm (seminal fluid).

The accumulating abnormal cells form a tumor that can grow to invade nearby tissue. In time, some abnormal cells can break away and spread (metastasize) to other parts of the body.

According to the Mayo Clinic, factors that can increase your risk of prostate cancer include:

Older age. Your risk of prostate cancer increases as you age. It's most common after age 50.

Race. For reasons not yet determined, Black people have a greater risk of prostate cancer than do people of other races. In Black people, prostate cancer is also more likely to be aggressive or advanced.

Family history. If a blood relative, such as a parent, sibling or child, has been diagnosed with prostate cancer, your risk may be increased. Also, if you have a family history of genes that increase the risk of breast cancer (BRCA1 or BRCA2) or a very strong family history of breast cancer, your risk of prostate cancer may be higher.

Obesity. People who are obese may have a higher risk of prostate cancer compared with people considered to have a healthy weight, though studies have had mixed results. In obese people, the cancer is more likely to be more aggressive and more likely to return after initial treatment.

The Mayo Clinic believes that people can reduce their risk of prostate cancer if they:

Choose a healthy diet full of fruits and vegetables. Eat a variety of fruits, vegetables and whole grains. Fruits and vegetables contain many vitamins and nutrients that can contribute to your health.

Whether you can prevent prostate cancer through diet has yet to be conclusively proved. But eating a healthy diet with a variety of fruits and vegetables can improve your overall health.

Choose healthy foods over supplements. No studies have shown that supplements play a role in reducing your risk of prostate cancer. Instead, choose foods that are rich in vitamins and minerals so that you can maintain healthy levels of vitamins in your body.

Exercise most days of the week. Exercise improves your overall health, helps you maintain your weight and improves your mood. Try to exercise most days of the week. If you're new to exercise, start slow and work your way up to more exercise time each day.

Maintain a healthy weight. If your current weight is healthy, work to maintain it by choosing a healthy diet and exercising most days of the week. If you need to lose weight, add more exercise and reduce the number of calories you eat each day. Ask your doctor for help creating a plan for healthy weight loss.

Talk to your doctor about increased risk of prostate cancer. If you have a very high risk of prostate cancer, you and your doctor may consider medications or other treatments to reduce the risk. Some studies suggest that taking 5-alpha reductase inhibitors, including finasteride (Propecia, Proscar) and dutasteride (Avodart), may reduce the overall risk of developing prostate cancer. These drugs are used to control prostate gland enlargement and hair loss.

However, some evidence indicates that people taking these medications may have an increased risk of getting a more serious form of prostate cancer (high-grade prostate cancer). If you're concerned about your risk of developing prostate cancer, talk with your doctor.

Note: Materials provided above by The Brighter Side of News. Content may be edited for style and length.

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